• Studies are looking at the role of adjuvant chemotherapy with Adriamycin , mitoxantrone , cisplatin , Cytoxan , carboplatin or progestational hormones in various doses and regimens .
Stage IIIa
This stage is defined by involvement of the uterine surface and/or the tubes and ovaries and/or the presence of malignant cells in the abdominal fluid (positive peritoneal washings).
Standard Treatment After surgery, any additional treatment is controversial and should be considered investigational. The chance of malignant cells being present within the abdominal cavity (Stage IIIa) increases with higher grades of cancer and with deeper invasion of the tumor into the uterine wall.
There is some controversy over the significance of malignant cells floating in the abdominal cavity, but most gynecologic oncologists recommend treatment with radiation therapy to the entire abdomen, intra-abdominal radioactive substances such as chromic phosphate, progestational hormone therapy or combination chemotherapy .
Which treatment is the most appropriate remains controversial because there is not enough information about the risk for recurrence and the prognosis .
